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A day old buffalo calf was presented with atresia ani and recto vaginal fistula to the Teaching Veterinary Clinical Complex, College of Veterinary Science, Proddatur. Under epidural anaesthesia the congenital defects were corrected surgically. The calf was treated post operatively with Ceftriaxone injection at the dose rate of 20 mg/kg for 5 consecutive days and Meloxicam injection at the dose rate of 0.3 mg/kg for 3 days. The correction of the condition, its management and successful recovery is reported.