Biochemical and haematological aspect of hypophosphatemia in pregnant Murrah buffaloes

Main Article Content

Shahzada Mudasir Rashid Insha Amin Rayees Ahmad Rahil Razak Shahzada Aadil Rashid Manzoor u Rahman

Abstract

Present study was conducted on 40 pregnant Murrah buffaloes belonging to Malwa region of Madhya Pradesh, India. Animals were divided into two groups, Group I (n=10) consisting of clinically healthy animals and Group II (n=30) consisting of hypophosphataemic animals with a history of passing coffee colored urine, reduced appetite and decreased milk production. Serum biochemical parameters divulged high mean concentration of serum glucose, bilirubin, total bilirubin, ALT and AST besides serum alkaline phosphatase, creatinine and blood urea nitrogen.  while as notably decreased levels of serum albumin, enzyme glucose-6 phosphate dehydrogenase (G6PD) and total serum protein . The blood mineral picture divulged elevated levels of potassium, molybdenum and iron whereas remarkably reduced concentrations of copper and phosphorous were recorded. Hematological studies revealed decreased red blood cells (RBC) count, hemoglobin( Hb) and packed cell volume (PCV) with increased erythrocyte sedimentation rate (ESR), neutrophil and lymphocyte count.

Article Details

How to Cite
RASHID, Shahzada Mudasir et al. Biochemical and haematological aspect of hypophosphatemia in pregnant Murrah buffaloes. Buffalo Bulletin, [S.l.], v. 40, n. 3, p. 389-397, sep. 2021. ISSN 2539-5696. Available at: <https://kuojs.lib.ku.ac.th/index.php/BufBu/article/view/157>. Date accessed: 26 oct. 2021.
Keywords
: hypophosphatemia, hemoglobinurea, Murrah, PPH, G6PD. Corresponding Author:
Section
Original Article

References

Akhtar, M., Z.A. Khan, M.Z. Khan and G. Muhammad. 2007. Haemato-Biochemical phosphates of Parturienthaemoglobinurea in buffalo. Turk. J. Vet. Anim. Sci., 31(2): 119-123.

Allen, J.D. and J.W. Gawthorne. 1987. Involvement of the solid phase of rumen digestation in interaction between copper, molybdenum and sulphur in sheep. Brit. J. Nutr., 58(2): 265-276. DOI: 10.1079/bjn19870094

Arif, M.N. 1997. Post parturient haemoglobinuria: (1) Comparative therapeutic efficacy of organic and inorganic phosphorus and, (II) some haematological alterations and urinalysis profiles. M.V.Sc. Thesis, Department Veterinary Clinical Medicine and Surgery, Faisalabad, Pakistan.

Benjamin, M.M. 1978. Outline of Veterinary Clinical Pathology, 3rd ed. Iowa State Univ. Press, Ames, Iowa, USA.

Bhardwaj, R.M., J.P. Rana and S.K. Chugh. 1988. Some erythrocytic enzymes in healthy and haemolobinuric buffaloes, p. 170-173. In Proceeding 2nd World Buffalo Congress, India.

Bhikane, A.U., M.S. Ali, B.W. Narladkarand and S.B. Kawithar. 1995. Post parturienthaemoglobinuria in crossed cow and itstreatment. Indian Vet. J., 72: 734-736.

Chugh, S.K., M.M. Maa and K.S. Malik. 1996. Lowered antioxidant status of red blood cells in post parturient haemoglobinuria of buffaloes. Vet. Rec. Commun., 22(6): 385-388. DOI: 10.1023/a:1006145328290

Cornelius, C.E. 1980. Liver functions. p. 201. In Kaneko, J.J. Clinical Biochemistry of Domestic Animals, 3rd ed. Academic Press, Inc. New York, USA.

Dhillon, K.S., J. Singh and R. Bajwa. 1972. Treatment of haemoglobinuria due to molybdenum induced phosphorus deficiency in buffaloes. Indian J. Anim. Sci., 42(12): 996-998.

Digraskar, S., B. Singh and D.N. Rajguru. 1996. Blood chemistry and therapeutic management of metabolic haemoglobinuria in buffaloes. Journal of Maharashtra Agricultural Universities, 21(1): 100-102.

El-Magawery, S., M.H. Nasr, M.Y. Naser and G.E. Abo El-Eneen. 1995. Clinicobiochemical and epididemiological aspects of Egyptain buffaloes. Indian Journal of Science, 66(11): 1123-1125.

Hoda, I.M. 2006. Clinico-Biochemical studies on hypophosphataemia in baffaloes with some therapeutic traits. Ph.D. Thesis, Faculty of Veterinary Medicine, Assiut University, Egypt.

Karapınar, T., M. Dabak and A. Kirbas. 2006. The detection and treatment of hemoglobinuria puerperal two cows. Research Journal of Eastern Anatolia, 2: 7-10.

Kurundkar, V.D., B.D. Deshpande, B. Singh and L.G. Ananwar. 1981. Biochemical and pathological changes in clinical cases of hemoglobinuria in buffaloes. Indian J. Anim. Sci., 51(1): 35-38.

Latimer, K.S., E.A. Mahaffey and K.W. Prasse. 2003. Duncan and Prasse’s Veterinary Laboratory Medicine: Clinical Pathology, 4th ed. Iowa State Press, Ames, Iowa, USA.

McDonald, P., R.A. Edwards, J.F.D. Greenbalgh and C.A. Morgan. 2002. Animal Nutrition, 6th ed. Pearson Education (Singapore) Pvt. Ltdl. Indian Banch, Delhi, India.

Pandey. N.N. and S.K. Misra. 1987. Clinic-biochemical studies of nutritional haemoglobinurea in buffalo and therapy. Indian Vet. J., 64(1): 39-43.

Pirzada, W.H. and S. Ali. 1990. Clinical case report of parturient haemoglobinuria in Nili-Ravi buffaloes (Bubalis bubalis). Pak. Vet. J., 40(1): 49-50.

Radostits, O.M., C.C. Gay, D.C. Blood and K.W. Hincheliff. 2000. Veterinary Medicine: A Text Book of the Disease of Cattle, Sheep, Pigs, Goats and Horses, 9th ed. Saunders, London, UK.

Sarwar, M. and Z.U. Hasan. 2001. Nutrient Metabolism in Ruminants. Friends Science Publishers, Faisalabad, Pakistan.

Sharma, K., M. Saravanan, P. Kumar, M. Kumar, R.K. Jadav and D.B. Mondal. 2014. Influence on haemato-biochemical and oxidative indices of post parturient haemoglobinurea (PHU) buffalo. Buffalo Bull., 33(4): 433-448. Available on: http://ibic.lib.ku.ac.th/e-bulletin/IBBU201404013.pdf

Singh, N., R. Kumari and M.A. Akbar. 1989. Biochemical changes in blood metabolites in buffaloes with indigestion. Indian Vet. J., 66(10): 923-926.

Smith, B.P. 1990. Internal Large Animal Medicine, 1st ed. C.V. Mosby Co., Philadelphia, USA. p. 1322-1324.
Spears, J.W. 2003. Trace mineral bioavailability in ruminants. J. Nutr., 133(5): 1506S-1509S. DOI: 10.1093/jn/133.5.1506S

Suttle, N.F. 1991. The interactions between copper, molybdenum and sulphur in ruminant nutrition. Annu. Rev. Nutr., 11: 121-140. DOI: 10.1146/annurev.nu.11.070191.001005