Anesthetic effects of ketamine-guaifenesin and isoflurane anesthesia for diaphragmatic herniorrhaphy in buffaloes

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Kherkar Trupti Thavardas Pitlawar Sanjeev Sahebrao Badgujar Chandravadan Lakshman Chaudhari Kamalakar Sudhakar


The study was undertaken on twelve buffaloes weighing 313 to 442 kg and age between 4 to 9 years to evaluate double drip of ketamine-guaifenesin and isoflurane anaesthesia for diaphragmatic herniorrhaphy. In Group I and II animals, anesthesia was induced with double drip of ketamine-guaifenesin (1000 mg of ketamine, 25 gm of guaifenesin in 500 ml Dextrose 5% solution) 1.5 ml/kg body weight. Double drip 2.5 mL/kg/h in Group I and 2 % isoflurane in Group II was used for maintenance of anaesthesia. In both the groups, quality of induction of anaesthesia was good to excellent. The quality of maintenance was assessed by analgesia, muscle relaxation, corneal reflexes, palpebral reflexes, and position of eyeball. Four animals in each group showed excellent muscle relaxation and two animals showed good muscle relaxation during the observation period. Analgesia was excellent in both the groups. In Group I three animals showed smooth and fast recovery whereas smooth and prolonged in rest of the animals. In Group II, all the animals showed smooth and fast recovery. The combination was found suitable for diaphragmatic herniorrhaphy in buffaloes.


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THAVARDAS, Kherkar Trupti et al. Anesthetic effects of ketamine-guaifenesin and isoflurane anesthesia for diaphragmatic herniorrhaphy in buffaloes. Buffalo Bulletin, [S.l.], v. 41, n. 2, p. 299-309, june 2022. ISSN 2539-5696. Available at: <>. Date accessed: 16 aug. 2022.
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