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The study revealed that the overall prevalence of bovine dermatological disorders was 25%. Specifically the prevalence of degnala disease was 14. Cultural isolation and identification of scrapes of the mouldy rice straw revealed Aspergillus flavus, Aspergillus niger, Pencillium notatum and Ochracious spp. The most prominent clinical signs observed in bovines with degnala disease were edematous swelling of the hind limbs, cracks on the skin of the limbs, ulcerative wounds at inter digital space of hooves and gangerene of the tail and ear tips. Haematological studies showed anemia and normal leukogram. Serum biochemical profile showed fall in blood urea nitrogen, albumin and normal serum zinc, copper and aspertate aminotransferase levels. However there was an increase in total protein values. Combination of Destrox, Chlorphenaramine maleate, Streptopencillin and Zinc oxide found to be useful in the treatment of degnala disease in bovines.