Efficacy of certain intrauterine immunomodulators in management of endometritis in postpartum graded Murrah buffaloes

Derangula Venkatesh; Kudikilla Venkataramana; Lakavath Ramsingh; Bommu Swathi

doi:10.56825/bufbu.2022.4113081

Authors

Derangula Venkatesh Department of Veterinary Gynaecology and Obstetrics, P.V. Narsimha Rao Telangana Veterinary University, Hyderabad, India
Kudikilla Venkataramana Department of Veterinary Gynaecology and Obstetrics, P.V. Narsimha Rao Telangana Veterinary University, Hyderabad, India
Lakavath Ramsingh Veterinary Clinical Complex, Korutla, India
Bommu Swathi Department of Veterinary Physiology, P.V. Narsimha Rao Telangana Veterinary University, Hyderabad, India

DOI:

https://doi.org/10.56825/bufbu.2022.4113081

Keywords:

Bubalus bubalis, buffaloes, endometritis, immunomodulators, bacterial load, conception rate

Abstract

The present study is conducted to evaluate the efficacy of certain immunomodulators on recovery and conception rate in post partum endometritic buffaloes. Total 50 buffaloes were selected for the study and randomly divided into five groups. The buffaloes of Group 1 were given with a single dose of 100 μg E. coli lipopolysaccharide as intrauterine, Group 2 buffaloes were treated with a single dose of 2 mg Lysozyme, Group 3 was treated with 4 g of Cephalexin for three consecutive days. While, Group 4 buffaloes were treated with a single dose of 2 mg Lysozyme + 4 g of Cephalexin and Group 5 was treated with 30 ml of normal saline and was kept as control. All therapeutics were infused into the uterus after dissolving in sterile water. The efficacy of treatment was assessed by declines in bacterial load and PMNL cell count after treatment. The overall conception rate was 88.88, 71.42, 66.66, 75.00 and 33.33% in Group 1, 2, 3, 4 and Group 5, respectively.

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Author Biographies

Derangula Venkatesh, Department of Veterinary Gynaecology and Obstetrics, P.V. Narsimha Rao Telangana Veterinary University, Hyderabad, India

derangulavenki.9@gmail.com

Kudikilla Venkataramana, Department of Veterinary Gynaecology and Obstetrics, P.V. Narsimha Rao Telangana Veterinary University, Hyderabad, India

Lakavath Ramsingh, Veterinary Clinical Complex, Korutla, India

Lakavath Ramsingh

Bommu Swathi, Department of Veterinary Physiology, P.V. Narsimha Rao Telangana Veterinary University, Hyderabad, India

Bommu Swathi

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