CLINICO-PHYSIOLOGICAL RESPONSE OF BUPIVACAINE ALONE AND IN COMBINATION WITH XYLAZINE AND PENTAZOCINE FOR LUMBAR EPIDURAL ANAESTHESIA IN BUFFALO CALVES

Govind Singh Nety; Raju Sharda; Rukmani Dewangan; Devendra Yadav; Shraddha Nety

doi:10.56825/bufbu.2025.4444279

Authors

Govind Singh Nety Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Durg, India
Raju Sharda Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Durg, India
Rukmani Dewangan Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Durg, India
Devendra Yadav Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Durg, India
Shraddha Nety Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Durg, India

DOI:

https://doi.org/10.56825/bufbu.2025.4444279

Keywords:

Bubalus bubalis, buffaloes, bupivacaine, buffalo calves, lumbar epidural, pentazocine, xylazine

Abstract

The present study was conducted during March 2014 to August 2014 on eighteen non descriptive buffalo calves ranging from 6 to 8 months to evaluate the clinico-physiological response of bupivacaine alone and in combination with xylazine and pentazocine for lumbar epidural anaesthesia. All the animals were subjected clinical examination before the start of anaesthetic study and the base values (0 minutes) for physiological parameters and ruminal movement were recorded as reference. The animals were randomly divided into three groups with six animals in each group viz. A, B and C on the basis of anaesthetic drugs used. In Group A- Bupivacaine alone 0.15 mg/kg, in Group B - Bupivacaine 0.15 mg/kg and Xylazine 0.05 mg/kg and in Group C-Bupivacaine 0.15 mg/kg and Pentazocine 0.5 mg/kg respectively, were administered at lumbar epidural space. The animals were observed by various clinical and physiological parameters. The clinical observation revealed an early onset of analgesia was in Group B followed by Group C and Group A. The depth of analgesia and areas of desensitization was deeper and better in Group B followed by Group C and then Group A. Motor incoordination showed earlier in Group B and C as compared to Group A. The score for onset of sedation was earlier in Group B animals as compared to Group A and C. Maximum duration of analgesia was recorded in animals of Group B followed by animals of Group C and Group A. Group B showed a significantly (P<0.01) late recovery as compared to Group C and Group A. A significant (P<0.05) decrease in heart rate and respiration rate in all the groups. Rectal temperature and ruminal movements showed decrease in Group A and C whereas significant (P<0.05) decrease in Group B. The transient changes in physiological parameters were compensated within 24 h. It is concluded that bupivacaine alone and in combination with xylazine and pentazocine can be used safely for lumbar epidural anaesthesia in buffalo calves.

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Author Biographies

Govind Singh Nety, Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Durg, India

Govind Singh Nety

dewanganrukmani@gmail.com

Raju Sharda, Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Durg, India

Raju Sharda

dewanganrukmani@gmail.com

Rukmani Dewangan, Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Durg, India

Rukmani Dewangan*

dewanganrukmani@gmail.com

Devendra Yadav, Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Durg, India

Devendra Yadav

dewanganrukmani@gmail.com

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