Patho-morphological and AgNOR based diagnosis of cutaneous squamous cell carcinoma in buffalo

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Satuti Sharma Shafiqur Rahman Nawab Nashiruddullah Shilpa Sood Riya Abrol


A case of cutaneous squamous cell carcinoma was reported in a 4 year old buffalo. Grossly, growth mass was 10 cm long, 7 cm width and 175 gm in weight and located on cranial aspect of left hind limb at fetlock joint. Histologically, the tumour showed irregular mass or cords of epidermal cells that proliferate downward and invade the dermis and sub-cutis. Keratin pearl formation also occurs at some places and it was composed of concentric layers of squamous cell gradually increasing keratinisation towards the centre. The value of mAgNOR and pAgNOR count for cutaneous squamous cell carcinoma was found to be 2.72±1.05 and 30%, respectively. On the basis of gross, histological examination and AgNOR count, the tumour was led to the final diagnosis of squamous cell carcinoma.


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SHARMA, Satuti et al. Patho-morphological and AgNOR based diagnosis of cutaneous squamous cell carcinoma in buffalo. Buffalo Bulletin, [S.l.], v. 40, n. 1, p. 199-204, mar. 2021. ISSN 2539-5696. Available at: <>. Date accessed: 18 apr. 2021.
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