Polymorphisms in the MTRN1A gene promoter in buffaloes in the Amazon

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Caio Santos Silva Ednaldo Silva Filho Maria Rosa Travassos da Rosa Costa Amanda de Sousa Matos Larissa Coelho Marques Rodrigo Lima Sales José Ribamar Felipe Marques

Abstract

The work aimed genetically to characterize the Murrah, Mediterranean and mixed-breed populations based on polymorphisms in the melatonin 1A receptor gene promoter (MTRN1A) and associate the genotypes with milk production. The haplotype A (position -1511 T and -1482 presents ACAA) and haplotype B (position -1511 C and -1482 does not present ACAA) were found in all groups. The haplotype frequencies were in Murrah breed (A=0.66 and B=0.34), Mediterranean breed (A=0.73 and B=0.27), and mixed-breed (A=0.65 and B=0.35). The Murrah breed had the genotypes AA (0.44), AB (0.44) and BB (0.12), and the Mediterranean and mixed-breed buffaloes had the genotypes AA (0.52) and (0.46), AB (0.42) and (0.39), and BB (0.06) and (0.15), respectively. For the Murrah, Mediterranean, and mixed-breed buffaloes, respectively, the expected heterozygosity values were 0.45, 0.40, and 0.45, the inbreeding coefficients were 0.04, -0.03, and 0.18, and the Hardy-Weinberg probabilities were 0.92, 0.24, and 0.59, respectively. The genotypes evaluated did not have an effect on milk production; however, the single nucleotide polymorphisms (SNP) and the insertion/deletion polymorphism (INDEL) can be used in studies on genetic variability.

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SILVA, Caio Santos et al. Polymorphisms in the MTRN1A gene promoter in buffaloes in the Amazon. Buffalo Bulletin, [S.l.], v. 40, n. 2, p. 293-299, june 2021. ISSN 2539-5696. Available at: <https://kuojs.lib.ku.ac.th/index.php/BufBu/article/view/2936>. Date accessed: 25 july 2021.
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Original Article

References

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