WHOLE BLOOD TRANSFUSION AS AN ADJUNCT THERAPY IN BUBALINE PHOSPHOROUS DEFICIENCY HEMOGLOBINURIA

Authors

  • Yogeshwar Mohanrao Wankhede Department of Veterinary Clinical Medicine, College of Veterinary and Animal Science, Maharashtra Animal and Fishery Sciences University, Maharashtra, India
  • Ravindra Kaka Jadhav Department of Veterinary Clinical Medicine, College of Veterinary and Animal Science, Maharashtra Animal and Fishery Sciences University, Maharashtra, India
  • Anil Udhavrao Bhikane Maharashtra Animal and Fishery Sciences University, Maharashtra, India
  • Vishwas Mohanrao Salunke Krantisinha Nana Patil College of Veterinary Science, Maharashtra Animal and Fishery Sciences University, Maharashtra, India
  • Sambhaji Gulab Chavhan Department of Veterinary Pathology, College of Veterinary and Animal Science, Maharashtra Animal and Fishery Sciences University, Maharashtra, India
  • Nandkumar Zetingrao Gaikwad, Dr. Department of Veterinary Biochemistry, College of Veterinary and Animal Science, Maharashtra Animal and Fishery Sciences University, Maharashtra, India

DOI:

https://doi.org/10.56825/bufbu.2025.4425030

Keywords:

Phosphorus deficiency hemoglobinuria, buffaloes, whole blood transfusion, treatment

Abstract

Phosphorus deficiency hemoglobinuria is an economically important production disease of lactating and advanced pregnant buffaloes characterized by hemoglobinuria, hemolytic anemia and mortality in severe cases of anemia. In view of the high prevalence of phosphorus deficiency hemoglobinuria in buffaloes in study region, the present study was planned with objective to evaluate the efficacy of whole blood transfusion in Phosphorus deficiency hemoglobinuria affected buffaloes suffering from severe hemolytic anemia. A total of 12 buffaloes suffering from hemoglobinuria, hemolytic anemia, hypophosphatemia and negative for any hemoprotozoan infections were randomly divided into two Treatment groups (1 and 2). Group 1 buffalo were treated with standard treatment of Phosphorus deficiency hemoglobinuria while Group 2 buffaloes were treated with standard treatment of Phosphorus deficiency hemoglobinuria along with whole blood transfusion. Clinical and hematological parameters showed faster clinical improvement in Group 2 buffaloes with recovery rate of 100% compared to slower recovery in Group 1 buffaloes with recovery rate of 83.33%. At study interval of 12 h post-treatment, Group 2 buffaloes showed increase in values of hemoglobin and PCV compared to Group 1 buffaloes. So, it is concluded that whole blood transfusion can be used as adjunct therapy in buffaloes suffering from Phosphorus deficiency hemoglobinuria to increase the recovery rate and survival rate.

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Author Biographies

Yogeshwar Mohanrao Wankhede, Department of Veterinary Clinical Medicine, College of Veterinary and Animal Science, Maharashtra Animal and Fishery Sciences University, Maharashtra, India

Yogeshwar Mohanrao Wankhede

Ravindra Kaka Jadhav, Department of Veterinary Clinical Medicine, College of Veterinary and Animal Science, Maharashtra Animal and Fishery Sciences University, Maharashtra, India

Ravindra Kaka Jadhav*

Anil Udhavrao Bhikane, Maharashtra Animal and Fishery Sciences University, Maharashtra, India

Anil Udhavrao Bhikane
Maharashtra Animal and Fishery Sciences University, Maharashtra, India

Vishwas Mohanrao Salunke, Krantisinha Nana Patil College of Veterinary Science, Maharashtra Animal and Fishery Sciences University, Maharashtra, India



Sambhaji Gulab Chavhan, Department of Veterinary Pathology, College of Veterinary and Animal Science, Maharashtra Animal and Fishery Sciences University, Maharashtra, India

Sambhaji Gulab Chavhan

Nandkumar Zetingrao Gaikwad, Dr., Department of Veterinary Biochemistry, College of Veterinary and Animal Science, Maharashtra Animal and Fishery Sciences University, Maharashtra, India

Nandkumar Zetingrao Gaikwad

References

Balcomb, C. and D. Foster. 2014. Update on the use of blood and blood products in ruminants. Vet. Clin. North N. Am. Food A., 30(2): 455-474. DOI: 10.1016/j.cvfa.2014.04.001

Bell, G. 2006. Blood transfusions in cattle. Brit. Vet. J., 11(3): 1-4. DOI: 10.1111/j.2044-3870.2006.tb00024.x

Bhikane, A.U. and A.M. Syed. 2014. Recent trends in management of metabolic disorders of transition cows and buffaloes. Intas Polivet, 15(2): 485-496.

Bhikane, A.U., L.G. Anantwar, A.P. Bhokre and B.W. Narladkar. 2004. Incidence, clinico-pathology and treatment of haemoglobinuria in buffaloes. Indian Vet. J., 81(2): 192-197.

Dhonde, S.N., S.U. Digraskar and V.V. Chavan. 2007. Phosphorous deficiency haemoglobinuria in buffaloes (Bubalus bubalis). Intas Polivet, 8(2): 282-386.

Divers, T.J. 2005. Blood component transfusions. Vet. Clin. N. Am. Food A., 21(3): 615-662. DOI: 10.1016/j.cvfa.2005.06.001

Digraskar, S., B. Singh and B.B. Deshpande. 1991. Epidemiology and clinico-pathology of haemoglobinuria in buffalo. Livestock Adviser, 16(12): 32-38.

Gautam, O.P., K.S. Malik, M.C. Nagpal and R.M. Sharma. 1972. Phosphorous deficiency haemoglobinuria in buffaloes in India. Haryana Agricultural University Journal of Research, 2(4): 270-277.

Gupta, S.R., D.K. Bihani, A.P. Singh, R.K. Tanwar and Fakhruddin. 2010. Clinical studies on post-parturient haemoglobinuria in buffaloes. Vet. Pract., 11(2): 127-129.

Hunt, E. and B. Wood. 1999. Use of blood and blood products. Vet. Clin. N. Am. Food A., 15(3): 641-662. DOI: 10.1016/s0749-0720(15)30168-7

Khan, A. and M.Z. Akhtar. 2007. Hemato-biochemical and clinico-epidemiological aspects of parturient hemoglobinuria in Nili-Ravi buffaloes. Ital. J. Anim. Sci., 6(2): 953-956. DOI: 10.4081/ijas.2007.s2.953

Kumar, C.P., G. Praveena and N.M. Sundar. 2014. Clinical management of acute post-parturient haemoglobinuria in a graded Murrah buffalo. Intas Polivet, 15(2): 531-534.

Kumar, R. 2017. Blood transfusion in veterinary medicine. Hematology and Transfusion International Journal, 4(4): 116-122. DOI: 10.15406/htij.2017.04.00093

Kumar, A., V. Thakur, S. Potliya, H. Singh, S. Ruhil, A. Ganguly, B.R. Maharana and R.S. Bisla. 2019. Study on incidence, haemato-biochemical changes and therapeutic management of post-parturient haemoglobinuria in Murrah buffaloes. Pharma Innovation Journal, 8(1): 147-150. Available on: https://www.thepharmajournal.com/archives/2019/vol8issue1/PartC/7-12-79-199.pdf

Mahmood, A., M.A. Khan, M. Younus, M.A. Khan, H.J. Iqbal and A. Ahad. 2012. Case-control study of parturient haemoglobinuria in buffaloes. Pak. Vet. J., 32(3): 375-377. Available on: https://www.pvj.com.pk/pdf-files/32_3/375-377.pdf

Pirzada, W.H. and S.Z. Hussain. 1998. Parturient haemoglobinuria in buffaloes- A review. Trop. Anim. Health Prod., 30(4): 209-215.

Samad, A., B. Singh and O.P. Qureshi. 1979. Some biochemical and clinical aspects of haemoglobinuria in buffaloes. Indian Vet. J., 56: 230-232.

Samad, A. and H.A. Malik. 1996. Pathogenesis of phosphorus deficiency haemoglobinuria in buffaloes II: Haemolysis mediated through low cellular ATP. Buffalo J., 1: 85-93.

Sarma, K., M. Saravanan, P. Kumar, M. Kumar, R.K. Jadav and D.B. Mondal. 2014. Influence on haemato-biochemical and oxidative indices of post-parturient haemoglobinuric (PPH) buffalo. Buffalo Bull., 33(4): 443-448. Available on: https://kukrdb.lib.ku.ac.th/journal/BuffaloBulletin/search_detail/result/288712

Shah, N.D., A.U. Bhikane, R.K. Jadhav and S.G. Chavhan. 2021. Efficacy of whole blood transfusion as an adjunct therapy in severe cases of haemolytic anaemia in cattle. Indian J. Anim. Res., DOI: 10.18805/IJAR.B-4565. DOI: 10.18805/IJAR.B-4565

Soldan, A. 1999. Blood transfusion in cattle. Practice, 21: 590-595. DOI: 10.1136/inpract.21.10.590

Wankhede, Y.M., R.K. Jadhav, A.U. Bhikane, S.G. Chavhan and K.S. Kedar. 2021. Clinical, epidemiological and haemato-biochemical aspects of bubaline phosphorus deficiency haemoglobinuria. Haryana Veterinarian, 60(2): 223-227.

Wang, X.L., C.H. Gallagher, T.J. McClure, V.E. Reeve and P.J. Canfield. 1985. Bovine post-parturient haemoglobinuria: Effect of inorganic phosphate on red cell metabolism. Res. Vet. Sci., 39(3): 333-339.

Same buffalo able to stand and walk immediately after whole blood transfusion.

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Published

2025-06-30

How to Cite

Wankhede, Y. M., Jadhav, R. K., Bhikane, A. U., Salunke, V. M., Chavhan, S. G., & Gaikwad, N. Z. (2025). WHOLE BLOOD TRANSFUSION AS AN ADJUNCT THERAPY IN BUBALINE PHOSPHOROUS DEFICIENCY HEMOGLOBINURIA. Buffalo Bulletin, 44(2), 129–139. https://doi.org/10.56825/bufbu.2025.4425030

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