IMPACT OF VARIOUS DIAGNOSTIC APPROACHES ON THE MANAGEMENT OF PRIMARY KETOSIS IN A MURRAH BUFFALO

Abstract

Five-year-old female Murrah buffalo was presented to the Madras Veterinary College Teaching Hospital with the history of anorexia for past four days, reduced milk production and animal calved fifteen days back. The physical examination revealed emaciation, tucked up udder and congested mucous membrane. Haemato-biochemical analysis revealed reduced blood glucose level (26 mg/dl), increased β-hydroxybutyrate (BHB) value (2.1 mmol/L) and triglycerides level (78.5 mg/dl). Venous blood gas (VBG) analysis showed increased pH, low potassium and chloride levels. Urinalysis (Keto-Diastix strip test) revealed ketone bodies (+++) in the urine. Ultrasound examination showed hyperechoic pattern of periportal regions in the liver. Based on biochemical, urinalysis, ultrasonography and VBG the case was diagnosed as primary ketosis. The animal was initially treated with intravenous infusion of 20% Dextrose with multiple electrolytes, oral propylene glycol and other supplements. Gradual clinical recovery was noticed after one week.