EFFECT OF LYSINE AND SODIUM BUTYRATE SUPPLEMENTATION ON METABOLIC PROFILE AND GROWTH PERFORMANCE OF BUFFALO CALVES
DOI:
https://doi.org/10.56825/bufbu.2025.4435194Keywords:
Bubalus bubalis, buffaloes, growth, lysine, metabolic profile, sodium butyrateAbstract
The present study was designed to support the calf growth during winter season with supplementation of crude protein, lysine (the essential amino acid) and sodium butyrate (acidifier) in the calf starter. 15 apparently healthy and infection free buffalo calves above 2 weeks of age were randomly divided into three groups: Group 1: calves were fed calf starter (20% CP), Group 2: calves were fed calf starter (20% CP) + lysine 100 g/100 kg calf starter, Group 3: calves were fed calf starter (20% CP) + lysine 100 g/100 kg calf starter + sodium butyrate -0.3%. Lysine and sodium butyrate were supplemented for 2 months. Group 3 calves (supplemented with lysine and sodium butyrate) exhibited significantly higher body weight value, withers height, length and heart girth as compared to Group 1 calves (Control). The data revealed no significant (P<0.05) effect of sodium butyrate and lysine on Hb, PCV, Liver function tests (Bilirubin, AST, ALT, ALKP, GGT) and Kidney function tests (BUN, Creatinine), total protein, glucose, sodium, chloride, potassium, plasma osmolality and total immunoglobulins.
Downloads
Metrics
References
Araujo, G., M. Terré, A. Mereu, I.R. Ipharraguerre and A. Bach. 2015. Effects of supplementing a milk replacer with sodium butyrate or tributyrin on performance and metabolism of Holstein calves. Anim. Prod. Sci., 56(11): 1834-1841. DOI: 10.1071/AN14930
Dillane, P., L. Krump, A. Kennedy, R.G. Sayers and G.P. Sayers. 2018. Establishing blood gas ranges in healthy bovine neonates differentiated by age, sex, and breed type. J. Dairy Sci., 101(4): 3205-3212. DOI: 10.3168/jds.2017-13445
Gajera, A.P., K.S. Dutta, D.K. Parsana, H.H. Savsani, M.D. Odedra, P.U. Gajbhiye and J.A. Chavda. 2013. Effect of bypass lysine, methionine and fat on growth and nutritional efficiency in growing Jaffrabadi heifers. Vet. World, 6(10): 15-18. DOI: 10.14202/vetworld.2013.766-769
Gorka, P., Z. Kowalski, P. Pietrzak, A. Kotunia, R. Kiljanczyk, J. Flaga and R. Zabielski. 2009. Effect of sodium butyrate supplementation in milk replacer and starter diet on rumen development in calves. J. Physiol. Pharmacol., 60(Suppl 3): 47-53.
Guilloteau, P., R. Zabielski, J.C. David, J.W. Blum, J.A. Morisset, M. Biernat and Y. Hamon. 2009. Sodium-butyrate as a growth promoter in milk replacer formula for young calves. J. Dairy Sci., 92(3): 1038-1049. DOI: 10.3168/jds.2008-1213
Kaneko, J.J. 1997. Serum proteins and disproteinemias, p. 117-138. In Kaneko, J.J., J.W. Harvey and M.L. Bruss. (eds). Clinical Biochemistry of Domestic Animals, Academic Press, San Diego, USA. DOI: 10.1016/B978-012396305-5/50006-3
Koenig, G. and S. Seneff. 2015. Gamma-glutamyltransferase: a predictive biomarker of cellular antioxidant inadequacy and disease risk. Dis. Markers, DOI: 10.1155/2015/818570
Kong, F., Y. Li, Q. Diao, Y. Bi and Y. Tu. 2021. The crucial role of lysine in the hepatic metabolism of growing Holstein dairy heifers as revealed by LC-MS-based untargeted metabolomics. Anim. Nutr., 7(4): 1152-1161. DOI: 10.1016/j.aninu.2021.10.001
Mudgal, V., N. Saxena, C. Mohan, S. Jain, K. Kumar, M.L. Sharma and R. Kumar. 2018. Precision feeding approach affecting growth, nutrient utilization, feed conversion efficiency and economics of feeding in weaned Murrah buffalo (Bubalus bubalis) calves. Indian J. Anim. Sci., 88(10): 1176-1179. DOI: 10.56093/ijans.v88i10.84151
Li, Y., Y. Bi, Q. Diao, M. Piao, B. Wang, F. Kong and Y. Tu. 2019. The limiting sequence and appropriate amino acid ratio of lysine, methionine, and threonine for seven- to nine-month-old Holstein heifers fed corn-soybean M-based diet. Animals, 9(10): 750. DOI: 10.3390/ani9100750
Liu, W., A.L.T.Z. La, A. Evans, S. Gao, Z. Yu, D. Bu and L. Ma. 2021. Supplementation with sodium butyrate improves growth and antioxidant function in dairy calves before weaning. J. Anim. Sci. Biotechnol., 12(1): 1-9. DOI: 10.1186/s40104-020-00521-7
Pearlin, B.V., S. Muthuvel, P. Govidasamy, M. Villavan, M. Alagawany, R. Farag and M. Gopi. 2020. Role of acidifiers in livestock nutrition and health: A review. J. Anim. Physiol. Anim. Nutr., 104(2): 558-569. DOI: 10.1111/jpn.13282
Sharma, U., D. Pal and R. Prasad. 2014. Alkaline phosphatase: An overview. Indian J. Clin. Biochem., 29(3): 269-278. DOI: 10.1007/s12291-013-0408-y
Vidyarthi, V.K. and C.K. Kurar. 2001. Influence of dietary butyrate on growth rate, efficiency of nutrient utilization and cost of unit gain in Murrah buffalo (Bubalus bubalis) male calves. Asian-Austral. J. Anim. Sci., 14(4): 474-478. DOI: 10.5713/ajas.2001.474
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Buffalo Bulletin

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.