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In the present study, the buffalo having surgical affections of claw were divided randomly in to two groups having six animals in each group. Tourniquet was placed circumferentially at the middle of the metacarpus in Group I (standard IVRA) and just below dewclaw in Group II (modified IVRA) animals. In Group I animals, lignocaine hydrochloride and dexmedetomidine mixture was injected 4 mg/kg and 5 µg/kg b.wt in the radial vein. However, in Group II above drugs were injected in half doses in the axial digital vein. Heart rate and respiration rate decreased significantly in both group of animals. In Group I pulse rate decreased significantly (P<0.05). After removal of tourniquet no significant changes in HR, PR and RR was observed in both groups of animals. Peripheral oxygen saturation (%) decreased significantly in both groups of animals even after removal of tourniquet. Systolic and diastolic pressure significantly (P<0.05) decreased in both group of animals. Mean arterial pressure decreased significantly (P<0.05) in both groups at 5 and 10 minutes interval. In Group II animals, the value increased significantly at 20 and 40 minutes interval. Sensory and motor block onset time was lower in Group II as compared to Group I animals. SBRT was more in Group II animals and MBRT was more or less similar in both groups. None of the animal of both group showed sign of toxicity except stumbling in 4 animals of Group I just after release of tourniquet.
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