Therpeutic efficacy evaluation of commonly used antitrypanosomal drugs in naturally infected buffaloes

Authors

  • Ashish Pratap Singh Department of Veterinary Medicine, College of Veterinary Science and Animal Husbandry, Uttar Pradesh Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go Anusandhan Sansthan, Uttar Pradesh, India
  • Arvind Kumar Tripathi Department of Veterinary Medicine, College of Veterinary Science and Animal Husbandry, Uttar Pradesh Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go Anusandhan Sansthan, Uttar Pradesh, India
  • Rudra Pratap Pandey Department of Veterinary Medicine, College of Veterinary Science and Animal Husbandry, Uttar Pradesh Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go Anusandhan Sansthan, Uttar Pradesh, India
  • Ashish Srivastava Department of Veterinary Medicine, College of Veterinary Science and Animal Husbandry, Uttar Pradesh Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go Anusandhan Sansthan, Uttar Pradesh, India

Keywords:

Bubalus bubalis, buffaloes, therapeutic efficacy, anti-trypanosomal drugs, percent recovery, trypanosomosis

Abstract

In present investigation therapeutic efficacy of three most commonly used anti-trypanosomal drugs (isometamidium chloride hydrochloride, diminazine aceturate, and quinapyramine sulphate) were studied. Evaluations of therapeutic efficacy were assessed done on the basis of percent recovery assessment, hematological and biochemical alteration on day 0, day 7th and day 14th post treatment. All three drugs were found effective against the trypanosomosis in buffalo but the extent of improvement in terms of hematological values, biochemical values and percent recovery was observed maximum in the treatment with isometamidium chloride hydrochloride followed by diminazene aceturate and least with the quinapyramine sulphate.

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Author Biography

Arvind Kumar Tripathi, Department of Veterinary Medicine, College of Veterinary Science and Animal Husbandry, Uttar Pradesh Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go Anusandhan Sansthan, Uttar Pradesh, India

Assistant Professor, Department of Veterinary Clinical Medicine, COVSc, DUVASU, Mathura, UP, India. 281001

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Published

2021-03-26

How to Cite

Singh, A. P., Tripathi, A. K., Pandey, R. P., & Srivastava, A. (2021). Therpeutic efficacy evaluation of commonly used antitrypanosomal drugs in naturally infected buffaloes. Buffalo Bulletin, 40(1), 19–30. Retrieved from https://kuojs.lib.ku.ac.th/index.php/BufBu/article/view/823

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