Lion’s Mane mushroom (Hericium erinaceus) : extraction, purification and biological activity
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Abstract
Hericium erinaceus, an edible mushroom with medicinal value, has a long history of use in China and other oriental countries. Polysaccharides are considered to be one of the major bioactive compounds in H. erinaceus, which possesses immunomodulating, anti-cancer, antioxidant, gastroprotection and intestinal health promotion, neuroprotective, hepatoprotective, antihyperglycemic and hypolipidemic activities. The extraction process directly impacts the yield, quantity, and bioactivity of mushroom metabolites. Effective methods should maximize efficiency and maintain compound quality, though advanced technology can increase costs. Therefore, selecting an appropriate extraction process is crucial to align with the intended application. This article reviews various extraction methods, including solvent extraction, enzymatic extraction, supercritical carbon dioxide extraction, and ultrasonic extraction. The aim is to compare the extraction efficiency, types, and bioactivity of active compounds, as well as the purity of the extracts obtained from Lion's Mane mushroom (Hericium erinaceus).
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พีรบูรณ์ จังรุ่งโรจน์. “ผลของเมล็ดธัญพืชและความเข้มข้นของเกลือต่อการเจริญเติบโตและการผลิตสารออกฤทธิ์ทางชีวภาพของสันใยไมซีเลียมเห็ดหัวลิง (Hericium erinaceus)” [โครงการปัญหาพิเศษนี้เป็นส่วนหนึ่งของการศึกษาตามหลักสูตรวิทยาศาสตร์บัณฑิต]. กรุงเทพฯ: มหาวิทยาลัยธรรมศาสตร์; 2562.
อัจฉรา บุญโรจน์, จิรพร สวัสดิการ และ วัชรวิทย์ รัศมี. รายงานฉบับสมบูรณ์ เรื่อง โครงการวิจัยและพัฒนาการเพาะเห็ดหัวลิงในภาคตะวันออกของประเทศไทย. คณะเทคโนโลยีการเกษตร มหาวิทยาลัยราชภัฏรำไพพรรณี; 2558.